Maria E Figueiredo-Pereira Selected Research

9-deoxy-delta-9-prostaglandin D2

1/2020	PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice.
9/2018	Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets.
1/2018	Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease.
1/2016	Prostaglandin J2: a potential target for halting inflammation-induced neurodegeneration.
10/2012	cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons.
7/2009	Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice.
7/2009	Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells.
8/2006	Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates.
7/2006	Prostaglandin J2 alters pro-survival and pro-death gene expression patterns and 26 S proteasome assembly in human neuroblastoma cells.
5/2006	Prostaglandin J2 reduces catechol-O-methyltransferase activity and enhances dopamine toxicity in neuronal cells.

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Maria E Figueiredo-Pereira Research Topics

Disease

17	Inflammation (Inflammations) 04/2022 - 05/2003
12	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2018 - 07/2002
9	Alzheimer Disease (Alzheimer's Disease) 04/2022 - 07/2004
6	Neuroinflammatory Diseases 01/2020 - 01/2006
6	Parkinson Disease (Parkinson's Disease) 01/2019 - 07/2004
4	Neuroblastoma 07/2009 - 06/2005
3	Stroke (Strokes) 04/2022 - 01/2014
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2014 - 07/2004
2	Spinal Cord Injuries (Spinal Cord Injury) 01/2016 - 10/2012
1	Amyloid Plaque 04/2022
1	Asthma (Bronchial Asthma) 04/2022
1	Memory Disorders (Memory Loss) 01/2020
1	Gliosis 02/2018
1	Cognitive Dysfunction 02/2018
1	Ataxia (Dyssynergia) 01/2017
1	Down Syndrome (Down's Syndrome) 01/2016
1	Pathologic Processes 01/2016
1	Pick Disease of the Brain (Pick's Disease) 01/2016
1	Myocardial Infarction 09/2014
1	Encephalitis (Encephalitis, Rasmussen) 09/2014
1	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2014
1	Demyelinating Diseases (Demyelinating Disease) 01/2014
1	Brain Injuries (Brain Injury) 01/2014
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2013
1	Tauopathies 04/2013
1	Dehydration (Water Stress) 07/2009
1	Necrosis 10/2007

Drug/Important Bio-Agent (IBA)

12	UbiquitinIBA 04/2022 - 05/2003
12	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2022 - 05/2003
11	9-deoxy-delta-9-prostaglandin D2IBA 01/2020 - 06/2005
11	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2004
10	Ubiquitinated ProteinsIBA 01/2017 - 07/2002
7	ProstaglandinsIBA 01/2020 - 07/2004
4	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2020 - 01/2014
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2018 - 05/2003
2	Pharmaceutical PreparationsIBA 04/2022 - 02/2018
2	Prostaglandin D2IBA 09/2018 - 07/2009
2	Cyclooxygenase InhibitorsIBA 09/2018 - 01/2016
2	Amyloid (Amyloid Fibrils)IBA 01/2018 - 12/2007
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2016 - 09/2014
2	Protein AggregatesIBA 09/2013 - 07/2006
1	ibudilastIBA 04/2022
1	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 01/2020
1	CalciumIBA 01/2019
1	Ibuprofen (Motrin)FDA LinkGeneric 09/2018
1	Methamphetamine (Desoxyn)FDA LinkGeneric 02/2018
1	Protein Kinases (Protein Kinase)IBA 02/2018
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2018
1	Amyloid beta-PeptidesIBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2017
1	Amino Acids FDA Link 01/2016
1	EnzymesIBA 01/2016
1	PK 11195 (PK11195)IBA 09/2014
1	CalpainIBA 04/2013
1	ATP dependent 26S protease (26S proteasome)IBA 04/2013
1	Adenosine Triphosphate (ATP)IBA 04/2013
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 04/2013
1	cyclopentenoneIBA 07/2009
1	Cytotoxins (Cytolysins)IBA 07/2009
1	CaspasesIBA 07/2009
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 12/2007
1	RotenoneIBA 08/2006
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 07/2006
1	Cysteine (L-Cysteine)FDA Link 07/2006
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 05/2006
1	Phosphotransferases (Kinase)IBA 01/2006
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2006
1	CytokinesIBA 12/2004
1	Interleukin-1 (Interleukin 1)IBA 12/2004
1	delta(12)-prostaglandin J(2)IBA 07/2004
1	HydrolasesIBA 07/2004
1	Inflammation MediatorsIBA 07/2004

Therapy/Procedure

2	Therapeutics 09/2014 - 01/2006